Bennett Fertility Institute (BFI) offers pre-implantation genetic screening (PGS) and pre-implantation genetic diagnosis (PGD) to select patients undergoing in vitro fertilization (IVF)
PGS and PGD require IVF, a process in which eggs and sperm are place in the lab (“in vitro”). Following fertilization and development of embryos (fertilized eggs) for 5 days, the embryos, now known as blastocysts, are biopsied and then frozen. The cells from the embryos are then analyzed for genetic abnormalities. At a future date, only healthy embryos are transferred into the uterus.
PGS is indicated in the following circumstances:
- Patients age 35 or older
- Patients with history of two or more miscarriages
- Patients who had two or more failed IVF procedures (fresh or frozen)
- Patients with a male partner with severe sperm abnormalities
PGD is indicated in patients undergoing IVF who are at risk of having a child with severe disease due to the presence of genetic abnormalities in one or both spouses. Such abnormalities are usually due to single gene defects.
BFI patients or prospective patients should call 405-949-6060 for information about PGS or PGD.