Lung Transplant Criteria List

Potential recipients of lung transplants at the INTEGRIS Nazih Zuhdi Transplant Institute must meet the following lung transplant criteria to join the lung transplant list. Criteria for a lung transplant include:

Criteria list adapted from JHLT 2006; 25:745-755; early referral highly desirable

  • Physiological age < 70 (for all types of lung transplants)
  • Less than 50 percent two to three year life expectancy, or NYHA III / IV
  • Within 20 percent of ideal body weight
  • Rehabilitation potential, psychosocial stability
  • Abstinence from smoking > 6 months
  • Cancer free survival > 5 years
  • COPD
    • BODE index exceeding 5
    • Hospitalization for exacerbation with acute hypercapnia
    • Pulmonary hypertension or cor pulmonae
  • Cystic fibrosis, bronchiectasis
    • FEV1 < 30 percent or rapidly declining FEV1
    • Exacerbations of pulmonary disease requiring ICU
    • Increasing frequency of exacerbations
    • Recurrent hemoptysis not controlled by embolization
    • Refractory or recurrent pneumothorax
  • Pulmonary fibrosis
    • Referral at the time of diagnosis is recommended
  • Primary pulmonary hypertension
    • NYHA functional class III or IV
    • Rapidly progressive disease
  • Sarcoidosis, lymphangioleimyomatosis, eosinophilic granuloma
    • NYHA functional class III or IV

Contraindication to Lung Transplant

  • Inability to cooperate or comply with medical therapy
  • Absence of a consistent or reliable social support system
  • Untreatable advanced dysfunction of another major organ (kidney, heart, etc.)
  • Active malignancy within past 2 - 5 years
  • Bone marrow failure
  • HIV infection
  • Liver cirrhosis, chronic active hepatitis B or C infection

Referral Criteria for Other INTEGRIS Transplants

More Information On Our Lung Transplant Surgery Program



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